Bioresorbable Implantable Electronics

Bioresorbable electronic systems represent a new class of technology with potential to create high performance emerging devices that can be used in emergency medicine, recovery, and rehabilitation.These systems functions with programmed time period after insertion into the body. And then, materials consisting the systems dissolves completely. Wide-ranging options in sensing (e.g., temporal electrophysiology mapping, intracranial sensors for monitoring patients, and temporal biomarkers) and treatment (e.g., temporal pace maker and nerve stimulator) are now possible in devices that exhibit excellent biocompatibility.

Chronic Stable Implantable Electronics

High-resolution neural interfaces over a large area have previously been impossible owing to the infeasibility of connecting thousands of wires in the small intracranial space. Current systems have drawbacks associated with damage to tissue or gradual degradation of sensors and the structures are rigid and cannot deform continuously as a brain swollen by insult changes shape. This may induce local damage that injures the patient and impedes signal collection. Direct contact of sensors to tissue without encapsulation offers improved signal-to-noise ratios but may promote biofouling, degradation of electrodes and other biocompatibility issues. We develop new devices that integrate flexible Si nano-membrane transistors and report high-density capacitive neural interfaces using active conformal electronics (HDC). Neural sensing from significant areas of the brain at high spatial and temporal resolution is demonstrated and tested. A high-density multiplexed array of large number of electrodes covering a moderate area maintains conformal contact even with moderate volumetric changes to the substrate. HDC’s enabling technology will revolutionize understanding of motor circuits, decision making circuits, neuropsychiatric illness, and the complex interplay among them by enabling simultaneous recording and stimulation in large-area, distributed brain networks at high resolution.

Wearable Epidermal Electronics

Unlike traditional wafer-based biomedical devices, stretchable electronics that laminates onto the skin leads to conformal contact and adequate adhesion based on van der Waals interactions alone, in a manner that is mechanically invisible to the user. We develop systems incorporating electrophysiological, temperature, and strain sensors, as well as transistors, light-emitting diodes, photodetectors, radio frequency inductors, capacitors, oscillators, and rectifying diodes. Solar cells and wireless coils provide options for power supply.